Role of infection in bladder stone disease in children.

The urine from 180 children with bladder stone disease (BSD) was cultured for evidence of urinary tract infection. Fifty eight (22.2%) BSD children had positive urine culture. E. Coli was the commonest organism (52%) followed by B. Proteus (3 1%). There was a significant relationship (P<0.00l) between high urinary pH and growth of B. Proteus whereas E. Coli was positively correlated with lower urinary pH. On correlating urinary tract infection with surface constituents of analysed stones, uric acid was more commonly seen in sterile urine (P <0.05). On infrared spectroscopic analysis of calculi calcium phosphate occurred significantly more frequently (P <0.01) in the group with infected urine (JPMA34: 132, 1984).